Cell signaling is the general term for multitude of cellular protein interactions that convey the physiological and homeostatic state of the living cell to the cellís nucleus or even neighboring cells that ultimately results in a change or modulation of gene and protein expression within the cell and cellular population. Numerous proteins are involved from extracellular matrix proteins (ECM) and their receptors such as integrins and adhesion proteins to chemical or ligand binding cellular receptors and cytoskeletal proteins that convey the signals down the signaling pathways to the nucleus. Once at the nucleus, gene expression is governed by an increasingly complex web of transcription factors and epigenetic modifications that mediate everything from mRNA stability and synthesis to direct DNA access by the transcription machinery of the cell. Biosensis is proud to offer a large assortment of antibodies to important targets in neuronal and cellular signaling and gene expression. Whether it is homebox transcription factors, signaling cascade kinases or structural proteins like cytokeratins and peripherin we have you covered with reagents the work for your research.