| Catalogue No. |
C-1535-500 |
| Description |
Presenilin-2 (PSEN2) is a multi-pass membrane protein and component of the gamma-secretase complex. Defects in PSEN2 are a cause of Alzheimer disease type 4 (AD4), an autosomal dominant Alzheimer disease. (Ref:SWISS-Prot). |
| Batch No. |
See product label |
| Unit size |
500 µl |
| Antigen |
Mixture of two human Presenilin 2 peptides (319-330 and 349-360 aa). Both sequences are highly conserved in human, mouse and rat. |
| Sequence |
GEELEEEEERGV and YDPEMEEDSYDS |
| Other Names |
AD3LP; AD5; E5-1; STM-2; PSEN2; AD4; PS2; PSNL2; STM2; PS-2; |
| Accession |
P49810 PSN2_HUMAN; |
| Produced in |
Chicken |
| Applications |
WB and ELISA. Suggested dilution of 1:1,000 to 1:4,000. To minimise background staining, a higher concentration of detergent (such as Tween-20) is suggested in the dilution and washing steps. Biosensis recommends that the optimal working dilution should be determined by the end user. |
| Cross-reactivity |
Human, Mouse, Rat |
| Blast URL |
Click here |
| Form |
Liquid. PBS with 0.02% Sodium Azide |
| Storage |
Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months. |
| Expiry Date |
12 months after purchase |