Glial cells belong the the group of non-neuronal cells within the central nervous system (CNS) which includes microglia, astrocytes and oligodendrocytes. Besides their role in providing structural and nutritional support to neurons, recent advances in glia biology has shed light on many more important functions that glial cells fulfil, for instance guiding proper neuronal wiring in the developing organism and synaptic plasticity in the mature CNS. Additionally, microglial cells have emerged as central mediators of neuroinflammation, a condition which accompanies virtually every neurodegenerative disease.
Biosensis offers a wide range of antibodies to support your research into glia biology. Our products include markers for microglia (CD11b/OX42 antibody) and astrocytes (GFAP and S100-B) as well as antibodies against cell surface receptors (eg., TrkB) and messenger molecules (eg., chemokines and neurotrophic factors) that are involved in neuron-glia communication. Moreover, our ELISA kits will help you to accurately quantify important intracellular messenger molecules such as BDNF, fractalkine/CX3CL1, TNF-α and IGF-I.