| Catalogue No.: |
M-879-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Full recombinant human APG12, isoform 2, (1-74) with a GST tag. |
| Other Names: |
Autophagy-related protein 12, GENE NAMEs: ATG12, APG12, APG12L |
| Accession: |
ATG12_HUMAN |
| Description: |
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. APG12 is the human homolog of a yeast protein involved in autophagy. APG12 is conjugated to APG5. The APG12-ATG5 conjugate has an apparent molecular mass of 65 kDa. The C-terminal glycine of APG12 is conjugated to a central lysine (lys130) of APG5. Studies showed that over expression of APG3 facilitated formation of the APG12-APG5 conjugate, suggesting that APG3 cross-talks with the APG12 conjugation system. APG12 is ubiquitously expressed.
|
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB, and sandwich ELISA. |
| Specificity: |
Specificity has been confirmed by WB and direct ELISA against the antigen. |
| Cross-reactivity: |
Human. Other species have not been tested. |
| Blast it: |
To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG from PBS, pH 7.2. |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
