| Catalogue No.: |
M-803-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
The antigen was a partial recombinant protein of human ASCL1 (amino acids 137 to 237) with a GST tag. |
| Other Names: |
Achaete-scute homolog 1, HASH1, GENE NAME: ASCL1, ASH1 |
| Accession: |
ASCL1_HUMAN |
| Description: |
This protein plays a role in neuronal commitment and differentiantion in most regions of the CNS and of several neuronal lineages in the PNS. It is also essential for the generation of olfactory and autonomic neurons. The unprocessed precursor is 236 amino acids in length and 25.45KDa. ASCL1 contains one basic helix-loop-helix (bHLH) domain. It activates transcription by binding to the Ebox (5'-CANNTG-3') and efficient DNA binding requires dimerisation with other bHLH proteins. It forms a heterodimer with TCF3. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is reccommended for WB, ELISA and sandwhich ELISA. |
| Specificity: |
The specificity of this antibody was confirmed by WB and ELISA against the recombinant protein with the GST tag. GST tag alone was used as a negative control. |
| Cross-react: |
Human, other species have not been tested. |
| Blast it: |
If you would like to see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence (make sure that you are selecting the sequence that you are interested in, as the sequence may be the precursor rather than the mature protein for example) and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG in phosphate buffered saline, pH7.2, 150mM NaCl. |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20°C for higher stability or at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
