| Catalogue No.: |
M-809-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
This antibody was raised against a partial recombinant protein of human CAB2 (amino acids 213 to 301) with a GST tag. |
| Other Names: |
Voltage-dependent L-type calcium channel subunit beta-2, calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, GENE NAME: CACNB2 |
| Accession: |
CACB2_HUMAN |
| Description: |
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels aids the function of the calcium channel by increasing the peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CAB2 is a membrane protein that is expressed in all tissues. The unprocessed precursor is 660 amino acids in length and has a predicted molecular weight of 74.5KDa. It belongs to the calcium channel beta subunit family and contains one SH3 domain. CAB2 is involved in the MAPK signalling pathway and is also associated with Lambert-Eaton myasthenic syndrome. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is reccommended for WB, direct and sandwhich ELISA. The detection limit for recombinant CAB2 protein with GST tag is 0.1ng/ml when this antibody is used in sandwhich ELISA. |
| Specificity: |
The specificity of this antibody was confirmed by WB and ELISA against the recombinant GST tagged CAB2 protein. GST tag alone was used as a negative control. |
| Cross-react: |
This antibody cross reacts with human, mouse and rat CAB2 proteins. Other species have not been tested. |
| Blast it: |
If you would like to see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence (make sure that you are selecting the sequence that you are interested in, as the sequence may be the precursor rather than the mature protein for example) and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG in phosphate buffered saline, pH7.2 |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
