| Catalogue No.: |
M-823-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Partial recombinant protein of human Delta-1 (amino acids 18 to 109) with a GST tag. |
| Other Names: |
Delta-like protein 1, Drosophila Delta homolog 1, H-Delta-1, GENE NAME: DLL1 |
| Accession: |
DLL1_HUMAN |
| Description: |
Delta-1 acts as a ligand for Notch receptors. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting cells with the characteristics of a T-cel/NK-cell precursor. It is expressed in heart and pancreas, with lower expression in brain and muscle and very little expression in placenta, lung, liver and kidney. Delta-1 is a transmembrane protein which is ubiquinated by MIB, leading to its endocytosis and subsequent degradation. It contains one DSL domain and eight EGF-like domains. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB and sandwhich ELISA. |
| Specificity: |
The specificity of this antibody has been confirmed by WB and ELISA against the antigen. |
| Cross-react: |
Other species have not been tested. |
| Blast it: |
If you would like to see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence (make sure that you are selecting the sequence that you are interested in, as the sequence may be the precursor rather than the mature protein for example) and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG in phosphate buffered saline, pH7.4 |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20°C for higher stability or at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |