| Catalogue No.: |
M-827-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Partial recombinant protein of human D(2) dopamine receptor (amino acids 1 to 109) with a GST tag. |
| Other Names: |
Dopamine D2 receptor, GENE NAME: DRD2 |
| Accession: |
DRD2_HUMAN |
| Description: |
D(2) dopamine receptor is one of five (D1 to D5) receptors for dopamine. Its activity is mediated by G proteins which inhibit adenylyl cyclase. It interacts with GPRASP1, neurabin-2, CLIC6, CADPS and CADPS2. It is a transmembrane protein that belongs to the G-protein coupled receptor 1 family. The unprocessed precursor has a length of 443 amino acids and an estimated molecular mass of 50.6kDa. Genetic variations in DRD2 may determine the genetic susceptibility to alcoholism. A missense mutation in this gene causes myoclonus dystonia and several other defects in this gene are thought to be involved in psychiatric disorders, especially in schizophrenia. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB and direct ELISA. |
| Specificity: |
Specificity has been shown by WB and ELISA against the recombinant GST tagged D(2) dopamine receptor protein. |
| Cross-react: |
This antibody has not been tested against other species. |
| Blast it: |
If you would like to see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence (make sure that you are selecting the sequence that you are interested in, as the sequence may be the precursor rather than the mature protein for example) and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG in phosphate buffered saline, pH7.2 |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20°C for higher stability or at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
