| Catalogue No.: |
M-893-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Partial recombinant human HESR1 (121-221) with a GST tag. |
| Other Names: |
Hairy/enhancer-of-aplit related with YRPW motif protein 1, Hairy and enhancer of split-related protein 1, Hairy-related transcription factor 1, jHRT1, Cardiovascular helix-loop-helix factor 2, CHF-2, HES-related repressor protein 1, GENE NAMEs: HEY1, CHF2, HERP2, HESR1, HRT1 |
| Accession: |
HEY1_HUMAN |
| Description: |
HESR-1 belongs to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It binds preferentially to the canonical E box sequence 5\'-CACGTG-3\'. It represses transcription by the the cardiac transcriptional activators GATA4 and GATA6. HESR1 is expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB and sandwich ELISA. |
| Specificity: |
Specificity has been confirmed by WB and direct ELISA against the antigen. |
| Cross-react: |
Human. Other species have not been tested. |
| Blast it: |
To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG from PBS, pH 7.2. |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
