| Catalogue No.: |
M-914-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Recombinant human PhyH [1-338], with a GST tag. |
| Other Names: |
Phytanoyl-CoA dioxygenase peroxisomal, Phytanoyl-CoA alpha-hydroxylase, Phytanic acid oxidase, GENE NAMEs: PHYH, PAHX |
| Accession: |
PAHX_HUMAN |
| Description: |
PhyH is a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. It requires iron and ascorbate as cofactors and is expressed in liver, kidney, and T-cells but not in spleen, brain, heart, lung and skeletal muscle. Defects in PhyH are a cause of Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB and ELISA. |
| Specificity: |
Specificity has been confirmed by WB and ELISA against the antigen. |
| Cross-reactivity: |
Human. Other species have not been tested. |
| Blast it: |
To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG from PBS, pH 7.2. |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
