| Catalogue No. |
M-865-100 |
| Description |
Secretogranin-5 is an acidic protein of 186 amino aids and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion. |
| Batch No. |
See product label |
| Unit size |
100 µg |
| Antigen |
Partial recombinant human Secretogranin-5 (amino acids 59-160) with a GST tag. |
| Other Names |
Neuroendocrine protein 7B2, Secretory granule endocrine protein I, Secretogranin V, Pituitary polypeptide, GENE NAMEs: SCG5, SGNE1 |
| Accession |
7B2_HUMAN |
| Produced in |
Mouse |
| Purity |
Protein G purified immunoglobulin |
| Applications |
This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity |
Specificity has been confirmed by WB and direct ELISA against the antigen. |
| Cross-reactivity |
Human, mouse and rat. Other species have not been tested. |
| Blast it |
To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form |
Lyophilised mouse IgG from PBS, pH 7.2. |
| Reconstitution |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date |
12 months after purchase |
