| Catalogue No.: |
M-989-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
A recombinant neuronal NOS fragment from rat brain. |
| Other Names: |
neuronal NOS; nNOS; brain NOS; bNOS; NOS type 1; NOS1; NC-NOS; Constitutive NOS; |
| Accession: |
P29475 NOS1_HUMAN; P29476 NOS1_RAT; |
| Description: |
Nitric oxide synthase (NOS) catalyses the formation of nitric oxide, an important messenger molecule in functions such as homeostasis and synaptic plasticity. NOS is classified into three types: (1) neuronal NOS (nNOS) or brain NOS (bNOS) (2) inducible NOS (iNOS) or macrophage NOS (mNOS) and (3) endothelial NOS (eNOS). |
| Produced in: |
Mouse |
| Purity: |
IgG |
| Applications: |
Western Blotting (WB). A concentration of 0.5 µg/ml is recommended for WB. Human NOS (nNOS-1) has a predicted length of 1,434 residues and MW of 161 kDa. |
| Specificity: |
The specificity of this antibody has been confirmed by WB against the antigen. |
| Cross-reactivity: |
Human; rat; goat; pig; |
| Blast it: |
If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule.
The BLAST database can also be used to compare any amino acid sequence between species and between protein. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please choose carefully, as the sequence you choose may be a precursor rather than the mature protein for example. |
| Form: |
Liquid (0.5ml) in 50% glycerol, 0.9mg NaCl and 0.2mg Na2HPO4 |
| Reconstitution: |
The liquid formulation should be diluted in PBS (pH 7.4) |
| Storage: |
After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. |
| Expiry Date: |
12 months after purchase |