| Catalogue No.: |
M-842-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µg |
| Antigen: |
Recombinant human IL-6 protein with GST tag. |
| Other Names: |
Interleukin-6, B-cell stimulatory factor 2, BSF-2, Interferon beta-2, Hybridoma growth factor, CTL diffenrentiation factor, CDF, GENE NAME: IL6, IFNB2 |
| Accession: |
IL6_HUMAN |
| Description: |
IL-6 is a cytokine with many biological functions. Some of its roles include the final differentiation of B-cells into Ig-secreting cells, induction of meloma and plasmacytoma growth, induction of nerve cell differentiation, and in hepatocytes, induction of acute phase reactants. IL-6 is secreted and is N- and O-glycosylated post translationally. Genetic variations in IL-6 can be correlated with bone mineral density and low bone mineral density is a risk factor for osteoporosis. Defects in IL-6 are associated with juvenile rheumatoid arthritis and at least one polymorphism in IL-6 makes HIV-infected men susceptible to Kaposi sarcoma which is a relatively rare malignant tumour. |
| Produced in: |
Mouse |
| Purity: |
Protein G purified immunoglobulin |
| Applications: |
This antibody is recommended for WB, and ELISA. |
| Specificity: |
Specificity has been confirmed by WB and direct ELISA against the antigen. |
| Cross-reactivity: |
Human. Other species have not been tested. |
| Blast it: |
To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised mouse IgG in phosphate buffered saline, pH7.2 |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date: |
12 months after purchase |
