biosensis fine bioscience tools - antibodies, elisa kits, proteins, toxins and peptides An Australia-US partnershipPhone: 1800 605 5127 in the US, or +61 8 8352 7711 for international enquiries to Australia.
HomeAbout BiosensisBiosensis distributorsResourcesHelp deskordering from BiosensisContact us
 


Technical Notes
 
View our tech notes
 
 
Follow us...
 
Google+ Follow us on Twitter

Find us on Facebook

Sign up for Biosensis newsletters
Visit our newsletter archive
 
 
News and Site Information.

Revealing the role of p75-ICD in retrograde pro-apoptotic signal


08/17/2018


Bruce Carter and his laboratory have been studying neurotrophin signalling for decades and the latest paper from his laboratory provides further details of the mechanism by which neurotrophic factor deprivation leads to p75 proteolysis and retrograde transport of the degenerative signal that leads to neuronal death.


From the Laboratory of Bruce Carter (Developmental Cell. Pathak et al., 2018). Figure courtesy of Developmental Cell.

Biosensis - Novel antibody available for p75NTR research
 
New clone 8J2 to the extracellular domain of p75NTR (cat# M-1818-100), ideal for:

·    In vivo targeting: retrograde tracing and receptor trafficking
·     Flow cytometry, immunopanning, western blot, immuohistochemistry and more
·     Most mammalian species, including human, mouse and rat
·     Replaces popular MLR2 clone

 
For August only, get 15%* off this new mouse antibody clone. Quote: P75-August2018
 
Other quality NGFR/p75 products include the Biosensis p75ECD ELISA kits for human and mouse - the most sensitive and validated assay kits available.

*Direct orders only, limit one order per customer


Continue