ENC-1 is an actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. It is a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target protein. It is detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. It is highly exprssed in adult brain, especially in the hippocampus and amygdala, and spinal cord. It is dramatically up-regulated upon neuronal differentiation.
||See product label
||Partial recombinant human ENC-1 (amino acids 17-98) with a GST tag.
||Ectodermal-neural cortex protein 1; p53-induced gene 10 protein; Nuclear matrix protein NRP/B; ENC1; NRPB; PIG10
||Protein G purified immunoglobulin
||This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||Specificity has been confirmed by WB and direct ELISA against the antigen.
||Human. Other species have not been tested.
||To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
||Lyophilised from PBS pH 7.2
||Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
||After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
||12 months after purchase