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Mouse monoclonal antibody to human Paired box protein Pax-5 [8F9]: IgG

$297.00USD


Catalogue No. M-857-100
Description
Paired box protein Pax-5 is a member of the paired box (PAX) family of transcription factors. This family has a highly conserved DNA-binding motif known as the paired box. Paired box protein Pax-5 may play an important role in B-cell differentiation as well as neural development and spermatogenesis. It is involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. It localises to the nucleus and is expressed at early B-cell differentiation in the developing CNA and in adult testis. A defect in Paired box protein Pax-5 is a cause of acute lymphoblastic leukemia.
Batch No. See product label
Unit size 100 g
Antigen Partial recombinant human Paired box protein Pax-5 (192-302) with a GST tag.
Clone 8F9
Other Names B-cell-specific transcription factor; BSAP; PAX5
Accession PA1B3_HUMAN
Produced in Mouse
Purity Protein G purified immunoglobulin
Applications This antibody is recommended for WB, IHC and sandwich ELISA. The recommended dilution for this antibody is 1 g/ml for IHC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity Specificity has been confirmed by WB and direct ELISA against the antigen.
Cross-reactivity Human. Other species have not been tested.
Blast it To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
Form Lyophilised from PBS pH 7.2
Reconstitution Reconstitute in 100 l of sterile water. Centrifuge to remove any insoluble material.
Storage After reconstitution keep aliquots at -20C for higher stability or at 4C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Expiry Date 12 months after purchase
Images (click to zoom)
Mouse monoclonal antibody to human Paired box protein Pax-5 [8F9]: IgG
Immunohistochemical detection of Paired box protein Pax-5 on formalin fixed, paraffin-embedded, human tonsil tissue. Anti-Paired box protein Pax-5 primary antibody, catalogue number M-857-100, was used at a concentration of 1 µg/ml.
Mouse monoclonal antibody to human Paired box protein Pax-5 [8F9]: IgG Western blot detection of GST tagged recombinant Paired box protein Pax-5.
PDF Data Sheet

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MSDS

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