Semaphorin-3A is a secreted protein that induces the collapse and paralysis of neuronal growth cones. It could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. It Binds to the complex neuropilin-1/plexin-1. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
||See product label
||Partial recombinant human Semaphorin 3A (672-770) with a GST tag.
||Semaphorin III; Sema III; SEMA3A; SEMAD
||Protein G purified immunoglobulin
||This antibody is recommended for WB, and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||Specificity has been confirmed by WB and direct ELISA against the antigen.
||Human. Other species have not been tested.
||To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
||Lyophilised from PBS pH 7.4
||Reconstitute in 50 µl of sterile water. Centrifuge to remove any insoluble material.
||Store lyophilized antibody at 2-8ºC. After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
||12 months after purchase