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Mouse monoclonal to human Transcription factor HES-1 [4D9]: IgG

$297.00USD


Catalogue No. M-841-100
Description
Transcription factor HES-1 is a transcriptional repressor of genes that require a basic helix-loop-helix protein for their transcription. It needs to form a complex with a corepressor protein (Groucho) to repress transcription. Transcription factor HES-1 has a particular type of basic domain which contains a helix-interrupting proline, that binds to the N-box (CACNAG) rather than the canonical E-box (CANNTG). It also consists of a C-terminal WRPW motif that is necessary for the interaction with Groucho. It localises to the nucleus.
Batch No. Refer to product label
Unit size 100 g
Antigen Partial recombinant protein of human Transcription factor HES-1 (aa 36 to 143) with a GST tag.
Clone 4D9
Other Names Hairy and enhancer of split 1; Hairy-like; HHL; Hairy homolog; HES1; HL; HRY
Accession HES1_HUMAN
Produced in Mouse
Purity Protein G purified immunoglobulin
Applications This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity Specificity has been confirmed by WB and direct ELISA against the antigen.
Cross-reactivity Human. Other species have not been tested.
Blast it To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
Form Lyophilised from PBS pH 7.3
Reconstitution Reconstitute in 100 l of sterile water. Centrifuge to remove any insoluble material.
Storage After reconstitution keep aliquots at -20C for higher stability or at 4C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Expiry Date 12 months after purchase
Images (click to zoom)
Mouse monoclonal to human Transcription factor HES-1 [4D9]: IgG
Western blot analysis on human acute monocytic leukemia cell lysate using mouse monoclonal antibody to human Transcription factor HES-1, catalogue number M-841-100. This antibody detects a band at ~30KDa.

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MSDS

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