DRP-4 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as homotetramer and a heterotetramer. Antibodies against post-translationally modified DPR-4 are present in sera from patients with paraneoplastic neurological diseases.
||See product label
||Partial recombinant human DRP-4 (461-559) with a GST tag.
||Dihydropyrimidinase-relate protein 3; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP4 protein; DPYSL4; CRMP3; ULIP4
||This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||Specificity has been confirmed by WB and direct ELISA against the antigen.
||Human. Other species have not been tested.
||To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
||Liquid. 50% glycerol
||Keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
||12 months after purchase