biosensis fine bioscience tools - antibodies, elisa kits, proteins, toxins and peptides An Australia-US partnershipPhone: 1800 605 5127 in the US, or +61 8 8352 7711 for international enquiries to Australia.
HomeAbout BiosensisBiosensis distributorsResourcesHelp deskordering from BiosensisContact usFlyers
 


Technical Notes
 
View our tech notes
 
 
Follow us...
 
Google+ Follow us on Twitter

Find us on Facebook

Sign up for Biosensis newsletters
Visit our newsletter archive
 
 

Rabbit antibody to the Tyrosine Kinase Receptor C (TrkC): whole serum

$297.00USD


Catalogue No. R-151-100
Description TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3).? Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. ALTERNATIVE PRODUCTS: 4 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Mutations in TrkC have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Batch No. See product label
Unit size 100 uL
Antigen Extracellular domain of glycosylated human TrkC protein produced in CHO cells was used as the immunogen.
Other Names Tropomyosin-related kinase receptor; NT-3 growth factor receptor; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; GP145-TrkC; Trk-C; NTRK3; TRKC
Accession NTRK3_HUMAN
Produced in Rabbit
Purity Whole serum
Applications IHC. A dilution of 1:1000 to 1:3000 is recommended for this application. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity Specificity was demonstrated by immunohistochemistry. This antibody was used to stain cryostat sections of the rat peripheral sensory ganglia.
Cross-reactivity Reacts with human, rat and mouse TrkC. Other species have not yet been tested.
Form Lyophilised
Reconstitution Reconstitute in 100 uL of sterile water. Centrifuge to remove any insoluble material.
Storage After reconstitution keep aliquots at -20C for a higher stability, and at 2-8C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
References Zhang FX, et al. (2005) Brain Res. 1062 (1-2) pp. 92-100.
PDF Data Sheet

Click to download the data sheet - Click to download the Data Sheet

MSDS

Click to download the MSDS - Click to download the MSDS

Customers who bought this product also purchased
Mouse monoclonal antibody to human p75NTR [MLR2]: IgG2a
Mouse monoclonal antibody to human p75NTR [MLR2]: IgG2a
Rabbit antibody to ATG4B (APG4B): whole serum
Rabbit antibody to ATG4B (APG4B): whole serum
Rabbit antibody to ATG3: whole serum
Rabbit antibody to ATG3: whole serum
Rabbit antibody to ATG5: whole serum
Rabbit antibody to ATG5: whole serum
Rabbit antibody to AP-1 complex subunit beta-1 (11-29): whole serum
Rabbit antibody to AP-1 complex subunit beta-1 (11-29): whole serum
Rabbit antibody to MAP1LC3A : whole serum
Rabbit antibody to MAP1LC3A : whole serum

Offices in the USA and Australia
My Ice Bucket  
 
0 items
 
 
Currencies
 
  
 
 
Email This Page
 
 
Tell someone you know about this product.
 
 
We Accept PayPal
 
You can use secured services of paypal to send us money via our email account MODULE_PAYMENT_PAYPAL_IPN_IDYou can use secured services of paypal to send us money via our email account MODULE_PAYMENT_PAYPAL_IPN_IDYou can use secured services of paypal to send us money via our email account MODULE_PAYMENT_PAYPAL_IPN_ID
Click to make a payment


Official PayPal Seal