||Integrins are cell-surface proteins with important roles in cell adhesion, migration and cell surface mediated signalling. The integrin family contains at least 18 alpha and 8 beta subunits that form alpha/beta heterodimers. The integrin alpha-4 subunit is also known as CD49D. It associates with either beta-1 or beta-7 subunits to form receptors for fibronectin and VCAM1.
||See product label
||A synthetic peptide corresponding to a region (1014-1032 aa) from human Integrin alpha-4. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
||Integrin alpha-IV; VLA-4; CD49 antigen-like family member D; CD49d antigen; TGA4; CD49D; ITGA4;
||Affinity purified on antigen column
||Immunohistochemistry (IHC). A concentration of 1.0 µg/ml is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||The specificity of this antibody has been confirmed by IHC against the antigen.
||Human; rat; expected to react with mouse;
||Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
||Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material.
||At least 12 months after purchase at 2 - 4°C (lyophilized formulations).
After reconstitution, aliquot and store at -20°C for a higher stability and at 4°C with an appropriate antibacterial agent. Avoid freeze-thaw cycles.
||12 months after purchase