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Rabbit polyclonal antibody to human Presenilin-2 (319-334): Affinity purified

$297.00USD


Catalogue No. R-1479-100
Description Presenilin-2 is a multi-pass membrane protein and component of the gamma-secretase complex. At least 2 isoforms are produced by alternative splicing.
Batch No. See product label
Unit size 100 g
Antigen A synthetic peptide corresponding to a region (319-334 aa) from human Presenilin-2.
Antigen Location 319-334
Other Names PS-2; AD3LP; AD5; E5-1; STM-2; PSEN2; AD4; PS2; PSNL2; STM2;
Accession P49810 PSN2_HUMAN;
Produced in Rabbit
Applications Western Blotting (WB) and Immunohistochemistry (IHC). A concentration of 1.0 g/ml is recommended for WB. Human Presenilin-2 (isoform 1) has a predicted length of 448 amino acids and MW of 50 kDa. A concentration of 1.0 g/ml is recommended for IHC to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. A concentration of 1.0 g/ml is also recommended for IHC in frozen tissue. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity The specificity of this antibody has been confirmed by WB (Human, Rat) and IHC (Rat) against the antigen.
Antibody Against Presenilin-2
Cross-reactivity Human; rat; predicted to react with mouse due to sequence homology
Blast URL Click here
Form Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Appearance White powder
Reconstitution Reconstitute in 100 l of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.
Storage At least 12 months after purchase at 2 - 4C (lyophilized formulations). After reconstitution, aliquot and store at -20C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date 12 months after purchase
PDF Data Sheet

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MSDS

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