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Rabbit polyclonal antibody to mouse APPL2 (619-662): Whole serum

$297.00USD


Catalogue No. R-1332-100
Description APPL2 is an isoform of APPL1 with 54% identity in their protein sequences. APPL2 has a role in cell proliferation and embryonic development. Recently, it was shown that APPL2 regulates FSH signaling and acts as a negative regulator in adiponectin signaling.
Batch No. See product label
Unit size 100 l
Antigen Mouse APPL2 protein (amino acids: 619-662) conjugated to GST.
Other Names DCC-interacting protein 13-beta; Dip13-beta; Adapter protein containing PH domain; PTB domain and leucine zipper motif 2; APPL2; DIP13B;
Accession Q8NEU8 DP13B_HUMAN;
Produced in Rabbit
Purity Whole serum
Applications Western Blotting (WB) and Immunoprecipitation (IP). A dilution between 1:2500 and 1:5000 is recommended for WB. A concentration of 3 l/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Cross-reactivity This antiserum is known to recognise both mouse and human APPL2.
Blast URL Click here
Form Liquid. 15% glycerol
Storage Aliquot and store at -20C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date 12 months after purchase
References 1. Wang C. et al (2009) Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells J Biol Chem. 2009 Nov 13;284(46):31608-15.
Images (click to zoom)
Rabbit polyclonal antibody to mouse APPL2 (619-662): Whole serum Western blot analysis with Rabbit polyclonal antibody to mouse APPL2, catalog number R-1332-100. Tissue homogenates of mouse brain (B), liver (Li), muscle (M), fat (F), heart (H), kidney (K), spleen (S) and pancreas (P) were used and 30µg of protein was loaded in each lane. Image courtesy of Wang C. et al (2009) J Biol Chem.

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