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Rabbit antibody to VRL-1 (744-761): affinity purified

$190.00USD

Catalogue No.: R-078-50
Batch No.: See product label
Unit size: 50 µg
Antigen: A synthetic peptide (C-KNSASEEDHLPLQVLQSP) as part of rat VRL-1 protein (aa: 744-761) conjugated to KLH has been used as the immunogen.
Other Names: osm-9-like TRP channel 2; OTRPC2
Accession: VRL_RAT
Description: TISSUE SPECIFICITY: Ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level). PTM: N-glycosylated. PTM: Phosphorylated by PKA. SIMILARITY: Belongs to the transient receptor family. TrpV subfamily. SIMILARITY: Contains 3 ANK repeats.
Produced in: NZ white rabbit
Purity: Whole serum
Applications: IHC, Immunofluorescence, Western blot and Immunoblot. Recommended to be used at a concentration of 0.5-1 µg for these applications. This antiserum works superbly for immunohistochemistry on free-floating or paraffin embedded sections. The optimal working dilution should be determined by the end user.
Specificity: Immunohistochemical analysis in rat dorsal root ganglia and spinal cord indicates a high level of specificity for this antiserum. Specificity was also shown by Western blot.
Cross-react: This antibody is known to react with rat and human VRL-1.
Blast it: If you would like to use this product in another species other than those specified here, or to see the shared ID between the immunogen used here in different species and/or other molecules, simply copy the immunogen (from the Immunogen field) and paste it HERE and blast/format it. Note that, antisera raised against synthetic peptides are quite often very specific for that peptide ie, only one single amino acid difference may be enough to restrict the specificity to a particular molecule. Regardless, you can always contact us if you need assistance with this.
Form: Lyophilised
Reconstitution: Reconstitute in 50 µl of sterile water. Centrifuge to remove any insoluble material.
Storage: After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent.
Expiry Date: 12 months after purchase
References: 1. Caterina, et al., Nature 398, 436-41 (Apr 1, 1999).
2. Jahnel, et al., Eur J Biochem 270, 4264-71 (Nov, 2003).
3. Montell, et al., Mol Cell 9, 229-31 (Feb, 2002).
Related items: M-008-50, R-047-100, R-053-100, R-076-100, R-055-50, R-079-100, R-147-20
Images
Rabbit antibody to VRL-1 (744-761): affinity purified Immunohistochemical staining of Vanilloid Receptor Like Protein (VRL-1) in rat trigeminal ganglion using rabbit polyclonal antibody to rat VRL-1, catalogue number R-078-100.
Rabbit antibody to VRL-1 (744-761): affinity purified Immunohistochemical staining of Vanilloid Receptor Like Protein (VRL-1) in rat dorsal horn using rabbit polyclonal antibody to rat VRL-1, catalogue number R-078-100.
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