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Rabbit polyclonal antibody to Catenin gamma (8-22): Affinity purified

$267.00USD

Catalogue No.: R-1027-100
Batch No.: See product label
Unit size: 100 µg
Antigen: A synthetic peptide (EQPIKVTEWQQTYTY) corresponding to a region (8-22) from the N-terminus of human Catenin gamma.
Other Names: Junction plakoglobin; Desmoplakin; JUP; CTNNG; DP3;
Accession: P14923 PLAK_HUMAN;
Description: Catenin gamma, also known as Junction Plakoglobin, is a common junctional plaque protein. It is a cytoplasmic protein with soluble and membrane-associated forms. The presence of Catenin gamma in both the desmosomes and in the intermediate junctions suggests it has a role in the structure and function of submembranous plaques.
Produced in: Rabbit
Purity: Affinity purified on antigen column
Applications: Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/ml is recommended for WB. Human Catenin gamma has a predicted length of 745 residues and MW of 82 kDa. A concentration of 1.0-2.0 µg/ml is recommended to detect Catenin gamma in formalin fixed and paraffin embedded tissues. Antigen retrieval is required.
Specificity: The specificity of this antibody has been confirmed by WB and IHC against the antigen.
Cross-reactivity: Human; mouse; rat; rabbit;
Blast it: If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule. The BLAST database can also be used to compare any amino acid sequence between species and between protein. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please chose carefully, as the sequence you chose may be a precursor rather than the mature protein for example.
Form: Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 added as preservative
Reconstitution: Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.
Storage: At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date: 12 months after purchase
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