||CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils (Ref: SWISSPROT). Both microglia and astrocytes secrete CCL2/MCP-1.
||See product label
||A synthetic peptide corresponding to a region (24-36 aa) from human Monocyte chemotactic protein 1 (CCL2).
||C-C motif chemokine 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; MCAF; Monocyte chemotactic protein 1; MCP-1; Monocyte secretory protein JE; Small-inducible cytokine A2; CCL2; MCP1; SCYA2;
||Western Blotting (WB). A concentration of 1.0 µg/ml is recommended for WB. Human CCL2 has a predicted length of 99 amino acids and MW of 11 kDa. . Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||The specificity of this antibody has been confirmed by WB against the antigen.
||Monocyte chemotactic protein 1
||Human; rat; mouse;
||Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
||Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.
||At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
||12 months after purchase
||1. Ishizuka K. et al. Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer\'s disease. Psychiatry Clin Neurosci. 1997 Jun;51(3):135-8.
2. Van Der Voorn P. et al. Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions. Am J Pathol. 1999 Jan;154(1):45-51.