| Catalogue No. |
R-1479-100 |
| Description |
Presenilin-2 is a multi-pass membrane protein and component of the gamma-secretase complex. At least 2 isoforms are produced by alternative splicing. |
| Batch No. |
See product label |
| Unit size |
100 µg |
| Antigen |
A synthetic peptide corresponding to a region (319-334 aa) from human Presenilin-2. |
| Antigen Location |
319-334 |
| Other Names |
PS-2; AD3LP; AD5; E5-1; STM-2; PSEN2; AD4; PS2; PSNL2; STM2; |
| Accession |
P49810 PSN2_HUMAN; |
| Produced in |
Rabbit |
| Applications |
Western Blotting (WB) and Immunohistochemistry (IHC). A concentration of 1.0 µg/ml is recommended for WB. Human Presenilin-2 (isoform 1) has a predicted length of 448 amino acids and MW of 50 kDa. A concentration of 1.0 µg/ml is recommended for IHC to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. A concentration of 1.0 µg/ml is also recommended for IHC in frozen tissue. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity |
The specificity of this antibody has been confirmed by WB (Human, Rat) and IHC (Rat) against the antigen. |
| Antibody Against |
Presenilin-2 |
| Cross-reactivity |
Human; rat; predicted to react with mouse due to sequence homology |
| Blast URL |
Click here |
| Form |
Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 |
| Appearance |
White powder |
| Reconstitution |
Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material. |
| Storage |
At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. |
| Expiry Date |
12 months after purchase |
