| Catalogue No. |
R-1333-100 |
| Description |
PERK (PKR-like ER kinase) is a single-pass type I ER membrane protein with a stress-sensing luminal domain connected by a transmembrane segment to a cytoplasmic-kinase domain. |
| Batch No. |
See product label |
| Unit size |
100 µl |
| Antigen |
A recombinant peptide from mouse PERK. |
| Other Names |
Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; Eif2ak3; Pek; Perk; |
| Accession |
Q9Z2B5 E2AK3_MOUSE; |
| Produced in |
Rabbit |
| Purity |
Whole serum |
| Applications |
Western Blotting (WB) and Immunoprecipitation (IP). A dilution of 1:500 is recommended for WB. A dilution of 30 µl of antibody in a total reaction mixture of 500 µl is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Antibody Against |
PERK (PKR-like ER kinase) |
| Cross-reactivity |
This antiserum is known to recognise both phosphorylated and non phosphorylated mouse PERK. |
| Form |
Liquid. 50% glycerol |
| Storage |
Aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. |
| Expiry Date |
12 months after purchase |
| Specific References |
1. Bollo M. et al (2010) Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs PLoS One. 2010 Aug 5;5(8)
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