| Catalogue No.: |
S-071-100 |
| Batch No.: |
See product label |
| Unit size: |
100 µl |
| Antigen: |
Human recombinant C-Reactive protein |
| Other Names: |
GENE NAME: CRP, PTX1 |
| Accession: |
CRP_HUMAN |
| Description: |
C-reactive protein has several roles associated with host defence such as; promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. Pentaxin (or Pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6. |
| Produced in: |
Sheep |
| Purity: |
Whole serum |
| Applications: |
WB. Extremely high titre antibody. For western blot a dilution of 1: 10,000 to 1: 100000 is recommended. The optimal dilution should be determined by the end user. |
| Specificity: |
It has been shown to be specific for C-reactive protein by WB. |
| Cross-react: |
Human, other species have not yet been tested. |
| Blast it: |
If you would like to see the shared identity between different species or other proteins follow the link in Accession field, select then the sequence (make sure that you are selecting the sequence that you are interested in, as the sequence may be the precursor rather than the mature protein for example) and copy and paste it HERE and blast/format it. |
| Form: |
Lyophilised |
| Reconstitution: |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage: |
After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. |
| Expiry Date: |
12 months after purchase |
| References: |
1. Lei K.-J, et al. J. Biol. Chem. 260:13377-13383(1985).
2. Woo P, et al. J. Biol. Chem. 260:13384-13388(1985). |
| Related items: |
G-007-100 |
