Application DetailsThis antibody binds to the A2 adenosine receptor, a G-protein-coupled receptor for adenosine that, upon ligand binding, activates adenylyl cyclase. The antibody acts as an allosteric inhibitor.
TargetAdenosine receptor A2a
SpecificityThis antibody binds specifically to the human A2 adenosine receptor.
Scientific BackgroundThis chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. This antibody binds to the A2 adenosine receptor, a G-protein-coupled receptor for adenosine that, upon ligand binding, activates adenylyl cyclase. The antibody acts as an allosteric inhibitor.