Cadherin-5, Goat Polyclonal Antibody

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Catalog Number
G-1910

    Product Info

  • Product Name Cadherin-5, Goat Polyclonal Antibody
  • Product Description google Goat anti-Cadherin-5 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Alternative Names CDH5; cadherin 5, type 2 (vascular endothelium); 7B4; CD144; 7B4 antigen; VE-cadherin; cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cd144 antigen; endothelial-specific cadherin; vascular endothelial cadherin
  • Application(s) FC, Pep-ELISA
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Specificity Reacts with VE-cadherin (aa537-549) from Human.
  • Species Reactivity Human
  • Immunogen Description A synthetic peptide consisting of amino acids, C-TVKYGQFDREHTK
  • Conjugate Unconjugated
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Regulatory Status For research use only.

    Specifications

  • Product Description Goat anti-Cadherin-5 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Application(s) FC, Pep-ELISA
  • Application Details Western Blot (1-2 µg/mL), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Cadherin-5
  • Specificity Reacts with VE-cadherin (aa537-549) from Human.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide consisting of amino acids, C-TVKYGQFDREHTK
  • Sequence TVKYGQFDREHTK
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Format Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
  • Storage Instructions Upon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names CDH5; cadherin 5, type 2 (vascular endothelium); 7B4; CD144; 7B4 antigen; VE-cadherin; cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cd144 antigen; endothelial-specific cadherin; vascular endothelial cadherin
  • Uniprot Number P33151
  • Uniprot Number/Name P33151 (CADH5_HUMAN)
  • Scientific Background Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (PubMed:21269602). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (PubMed:10861224).
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Flow cytometry analysis: of paraformaldehyde fixed HeLa cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

    Citations & References