Product DescriptiongoogleGoat anti-E3 ubiquitin-protein ligase HECW2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Alternative NamesHECW2 HECT C2 and WW domain containing E3 ubiquitin protein ligase 2; NEDD4-related E3 ubiquitin ligase; NEDL2; KIAA1301 protein; EndoNEDD4; DKFZp686M17164; NEDL2;
Application(s)FC, Pep-ELISA
Antibody HostGoat
Antibody TypePolyclonal
SpecificityReacts with EndoNEDD4 / NEDL2 from Human.
Species ReactivityBovine (Predicted), Human, Mouse (Predicted), Rat (Predicted)
Immunogen DescriptionA synthetic peptide consisting of amino acids, ASSAREHLLFVRR-C
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Product DescriptionGoat anti-E3 ubiquitin-protein ligase HECW2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Application(s)FC, Pep-ELISA
Application DetailsFlow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetE3 ubiquitin-protein ligase HECW2
SpecificityReacts with EndoNEDD4 / NEDL2 from Human.
Target Host SpeciesHuman
Species ReactivityBovine (Predicted), Human, Mouse (Predicted), Rat (Predicted)
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, ASSAREHLLFVRR-C
SequenceASSAREHLLFVRR
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesHECW2 HECT C2 and WW domain containing E3 ubiquitin protein ligase 2; NEDD4-related E3 ubiquitin ligase; NEDL2; KIAA1301 protein; EndoNEDD4; DKFZp686M17164; NEDL2;
Scientific BackgroundE3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition(Uniprot).