Product DescriptiongoogleGoat anti-Methylcytosine dioxygenase TET2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Alternative NamesTet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2
Application(s)FC, Pep-ELISA
Antibody HostGoat
Antibody TypePolyclonal
SpecificityReacts with Tet2 (mouse) from Mouse.
Species ReactivityHuman, Mouse, Rat (Predicted)
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-QPSLTSAQINFSQT
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Product DescriptionGoat anti-Methylcytosine dioxygenase TET2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Application(s)FC, Pep-ELISA
Application DetailsFlow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetMethylcytosine dioxygenase TET2
SpecificityReacts with Tet2 (mouse) from Mouse.
Target Host SpeciesMouse
Species ReactivityHuman, Mouse, Rat (Predicted)
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-QPSLTSAQINFSQT
SequenceQPSLTSAQINFSQT
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesTet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2
Scientific BackgroundDioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT (Uniprot).