Methylcytosine dioxygenase TET2, Goat Polyclonal Antibody

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Catalog Number
G-1932

    Product Info

  • Product Name Methylcytosine dioxygenase TET2, Goat Polyclonal Antibody
  • Product Description google Goat anti-Methylcytosine dioxygenase TET2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Alternative Names Tet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2
  • Application(s) FC, Pep-ELISA
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Specificity Reacts with Tet2 (mouse) from Mouse.
  • Species Reactivity Human, Mouse, Rat (Predicted)
  • Immunogen Description A synthetic peptide consisting of amino acids, C-QPSLTSAQINFSQT
  • Conjugate Unconjugated
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Regulatory Status For research use only.

    Specifications

  • Product Description Goat anti-Methylcytosine dioxygenase TET2 Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Application(s) FC, Pep-ELISA
  • Application Details Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Methylcytosine dioxygenase TET2
  • Specificity Reacts with Tet2 (mouse) from Mouse.
  • Target Host Species Mouse
  • Species Reactivity Human, Mouse, Rat (Predicted)
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide consisting of amino acids, C-QPSLTSAQINFSQT
  • Sequence QPSLTSAQINFSQT
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Format Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
  • Storage Instructions Upon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Tet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2
  • Uniprot Number Q92539
  • Uniprot Number/Name Q92539 (LPIN2_HUMAN)
  • Scientific Background Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT (Uniprot).
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Flow cytometric analysis: paraformaldehyde fixed NIH3T3 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

    Citations & References