Application DetailsImmunohistochemistry (IHC) and Western Blotting (WB). A concentration of 2.0 µg/mL is recommended for WB. The predicted length of human Catenin gamma is 745 residues and a MW of 82 kDa. A concentration of 4.0 µg/mL is recommended to detect Catenin gamma in formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetCatenin gamma (junction plakoglobin)
SpecificityThe specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; chicken; rat
Target Host SpeciesChicken
Species ReactivityChicken, Human, Rat
Immunogen DescriptionFull length recombinant protein (chicken)
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsAt least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesJunction plakoglobin; Desmoplakin; JUP; CTNNG; DP3;
Scientific BackgroundCatenin gamma, also known as Junction Plakoglobin, is a common junctional plaque protein. It is a cytoplasmic protein with soluble and membrane-associated forms. The presence of Catenin gamma in both the desmosomes and in the intermediate junctions suggests it has a role in the structure and function of submembranous plaques.