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Growth-associated protein 43 (GAP-43), Mouse Monoclonal Antibody
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Catalog Number
M-980
- Product Name Growth-associated protein 43 (GAP-43), Mouse Monoclonal Antibody
- Product Description Mouse anti-Growth-associated protein 43 (GAP-43) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names Neuromodulin; GAP43; PP46; p57; B-50; F1; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat; chicken; snake
- Species Reactivity Chicken, Human, Mouse, Rat, Snake
- Immunogen Description GAP-43 protein from neonatal rat forebrain membranes
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Growth-associated protein 43 (GAP-43) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.5-1.0 µg/mL is recommended for WB. Human GAP-43 has a predicted length of 238 residues and MW of 25 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect GAP-43 in formalin fixed and paraffin embedded tissues as well as formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Growth-associated protein 43 (GAP-43)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat; chicken; snake
- Target Host Species Rat
- Species Reactivity Chicken, Human, Mouse, Rat, Snake
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name GAP-8A12
- Conjugate Unconjugated
- Immunogen Description GAP-43 protein from neonatal rat forebrain membranes
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Neuromodulin; GAP43; PP46; p57; B-50; F1; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50;
- Uniprot Number P07936
- Uniprot Number/Name P07936 (NEUM_RAT)
- Scientific Background GAP-43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells. It is also a major component of neuronal growth cones. GAP-43 is used to specifically label injured neurons and to score neuronal regeneration. This antibody reacts with the three known isoforms and to both kinase C phosphorylated and dephosphorylated forms of GAP-43.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.