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Neurofilament heavy polypeptide (NF-H), Mouse Monoclonal Antibody
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Catalog Number
M-848
- Product Name Neurofilament heavy polypeptide (NF-H), Mouse Monoclonal Antibody
- Product Description Mouse anti-Neurofilament heavy polypeptide (NF-H) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Neurofilament heavy polypeptide; Neurofilament triplet H protein; 200 kDa neurofilament protein; NEFH; KIAA0845; NFH
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human NF-H protein (263-364) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Neurofilament heavy polypeptide (NF-H) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Neurofilament heavy polypeptide (NF-H)
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 2E8
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human NF-H protein (263-364) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Neurofilament heavy polypeptide; Neurofilament triplet H protein; 200 kDa neurofilament protein; NEFH; KIAA0845; NFH
- Uniprot Number P12036
- Uniprot Number/Name P12036 (NFH_HUMAN)
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Scientific Background
Neurofilaments contain three intermediate filament proteins: L, M and H, which are involved in the maintenance of the neuronal caliber. NF-H has an important function in mature axons. NF-H is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Defects in NF-H are a cause of amyotrophic lateral sclerosis (ALS) which is a neurodegenerative disorder affecting upper and lower motor neurons and results in fatal paralysis.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
