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Variably charged protein X-A (VCX-A), Mouse Monoclonal Antibody
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Catalog Number
M-899
- Product Name Variably charged protein X-A (VCX-A), Mouse Monoclonal Antibody
- Product Description Mouse anti-Variably charged protein X-A (VCX-A) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Variable charge X-linked protein 3; Variably charged protein X-A; VCX-8r; Variable charge protein on X with eight repeats; VCX3A; VCX3; VCX8R; VCXA
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and ELISA against the antigen. Human, mouse and rat. Other species have not been tested.
- Species Reactivity Human, Mouse, Rat
- Immunogen Description Partial recombinant human VCX-A (2-100) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Variably charged protein X-A (VCX-A) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Variably charged protein X-A (VCX-A)
- Specificity Specificity has been confirmed by WB and ELISA against the antigen. Human, mouse and rat. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 6A3
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human VCX-A (2-100) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Variable charge X-linked protein 3; Variably charged protein X-A; VCX-8r; Variable charge protein on X with eight repeats; VCX3A; VCX3; VCX8R; VCXA
- Uniprot Number Q9NNX9
- Uniprot Number/Name Q9NNX9 (VCX3_HUMAN)
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Scientific Background
VCX-A is only expressed in testis and may play a role in spermatogenesis or in sex ratio distortion. It is a 186 amino acid peptide that has an estimated molecular weight of ~20 kDa. It was recently identified that VCX-A is an inhibitor of the decapping enzyme DCP2 and that it stabilised mRNA. It is a noncanonical cap-binding protein that binds to capped RNA but not cap structures lacking RNA. Defects in VCX-A are associated with some forms of X-linked nonspecific mental retardation.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
