Application DetailsThis antibody is recommended for WB and IHC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
SpecificityThe specificity of this antibody has been confirmed by WB and ELISA against the antigen. This antibody cross-reacts with mouse and rat.
Target Host SpeciesHuman
Species ReactivityHuman, Mouse, Rat
Immunogen DescriptionPartial recombinant protein of human catenin delta-2 (amino acids 1081 to 1190) with a GST tag.
Purity DescriptionProtein G purified immunoglobulin
FormatLyophilized from PBS pH 7
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
Storage InstructionsAfter reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesDelta-catenin; Neural plakophilin-related ARM-repeat protein; NPRAP; Neurojungin; GT24; CTNND2
Catenin delta-2 functions as a transcriptional activator when bound to ZBTB33. It may also be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. It is predominantly expressed in the brain and localises to the nucleus and cell junction. The unprocessed precursor has a length of 1225 amino acids and a predicted molecular weight of 132.7KDa. This protein is O-glycosylated. It is also phosporylated upon DNA damage. It belongs to the beta-catenin family and contains nine ARM repeats.