Product DescriptionMouse anti-Oligophrenin-1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
Application DetailsThis antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
SpecificitySpecificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
Target Host SpeciesHuman
Immunogen DescriptionPartial recombinant human Oligophrenin 1 (641-735) with a GST tag.
Purity DescriptionProtein G purified immunoglobulin
FormatLyophilized from PBS pH 7.2
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
Storage InstructionsAfter reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Oligophrenin1 stimulates GTP hydrolysis of members of the Rho family. It could activate GTPase targets that are known to affect cell migration and outgrowth of axons and dendrites. It is a 802 amino acid protein of estimated molecular mass of ~92 kDa that is expressed in the brain. Defects in Oligophrenin1 are the cause of mental retardation X-linked OPHN1-related (MRXSO).