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Proto-oncogene tyrosine-protein kinase receptor Ret (RET), Mouse Monoclonal Antibody
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Catalog Number
M-918
- Product Name Proto-oncogene tyrosine-protein kinase receptor Ret (RET), Mouse Monoclonal Antibody
- Product Description Mouse anti-Proto-oncogene tyrosine-protein kinase receptor Ret (RET) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names RET
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by direct ELISA against the antigen. Human.
- Species Reactivity Human
- Immunogen Description Partial recombinant human RET protein [361-458] with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Proto-oncogene tyrosine-protein kinase receptor Ret (RET) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Proto-oncogene tyrosine-protein kinase receptor Ret (RET)
- Specificity Specificity has been confirmed by direct ELISA against the antigen. Human.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG2a, kappa
- Clone Name 1C6
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human RET protein [361-458] with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.4
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names RET
- Uniprot Number Q9BTX6
- Uniprot Number/Name Q9BTX6 (Q9BTX6_HUMAN)
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Scientific Background
RET protein is a member of the cadherin superfamily. It is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. RET protein plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET protein are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
