Tools for detecting neuronal degeneration are essential for identifying mechanisms of neurodegenerative diseases and potential treatments. Biosensis' Fluoro-Jade C (FJC) Ready-to-Dilute (RTDTM) Stain Reagent has truly made an impact due to its ease-of-use, backed up by over 80 publications. For large-scale studies, Biosensis now offers FJC Powder-a cost-effective alternative for processing a large number of tissue sections. Detailed protocols are provided to ensure consistency and high-quality data.
Fluoro-Jade C (FJC) staining (green) of degenerating neurons in the CA3 region of the hippocampus in old diabetic rats. Blue: DAPI nuclear stain. Picture courtesy Picture courtesy of Dr. Wang and colleagues. Results of this study were published in Wang S. et al. (2020), Geroscience, PMID: 32696219.
Past Merck-Millipore-Sigma customers please note, our powder formats are equivalent to discontinued items AG310 (FJB) and AG325 (FJC).
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The Biosensis Team