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Goat antibody to Anti-Tet2 mouse (254-267): Affinity Purified

$347.00USD


Catalogue No. G-1932-100
Description Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT (Uniprot)
Batch No. See product label.
Unit size 100 ug
Antigen A synthetic peptide with sequence C-QPSLTSAQINFSQT, from the internal region of the protein sequence according to NP_001035490.2; NP_001333665.1.
Sequence QPSLTSAQINFSQT
Antigen Location Internal Region
Other Names Tet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2
Accession Q92539(TET2_MOUSE)
Produced in Goat
Purity Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Applications Flow Cytometry (10 ug/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Species Against Mouse
Cross-reactivity Not tested. Expected to react with rat
Form Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage Upon receipt, aliquot and store at -20C long-term. Store at 2-8C short-term (up to 2 weeks). Minimize freezing and thawing.
Expiry Date 12 months after purchase if unopened.
Images (click to zoom)
Goat antibody to Anti-Tet2 mouse (254-267): Affinity Purified Flow cytometric analysis: paraformaldehyde fixed NIH3T3 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

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MSDS

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