||Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed: 8003967, PubMed: 25205354). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (By similarity). Ref: uniprot.org
||See product label.
||Recombinant bovine arrestin-1 with the first 20 amino acids of the C-terminus truncated
||48 kDa protein; Retinal S-antigen1; S-AG; Rod photoreceptor arrestin
||Western blotting (1:5,000) and Immunohistochemistry (1:1,000). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||Reacts with pig and bovine material. Other species not yet tested. Antibody detects arrestin-1 protein only and does not cross-react with the other 3 arrestin molecules.
||Lyophilised from a solution containing PBS buffer pH 7.2-7.6 with 5 mM sodium azide as preservative.
||Spin vial briefly before opening. Reconstitute in 100 uL sterile water. Centrifuge to remove any insoluble material. Final buffer contains preservative.
||Store lyophilised antibody at 2-8C. After reconstitution divide into aliquots and store at -20C for long-term storage. Store at 2-8C short-term (up to 4 weeks). Avoid repetitive freeze/thaw cycles.
||12 months after purchase if unopened.