||DNA replication licensing factor MCM7 belongs to the MCM family of proteins. MCM7 is required for G1/S phase transition. It ensures the correct assembly of replication forks on chromosomal DNA and that the genome is replicated only once at each cell cycle. Overexpression of MCM7 has been found in human gastric tumors. At least 2 isoforms are produced by alternative splicing.
||See product label
||Recombinant human DNA replication licensing factor MCM7
||CDC47 homolog; MCM7; CDC47; MCM2;
||Western Blotting (WB). A concentration of 0.5-1.0 ug/mL is recommended for WB. Human MCM7 (isoform 1 precursor) has a predicted length of 719 residues and MW of 81 kDa.
||The specificity of this antibody has been confirmed by WB against the antigen.
||If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule.
The BLAST database can also be used to compare any amino acid sequence between species and between protein. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please choose carefully, as the sequence you choose may be a precursor rather than the mature protein for example.
||Lyophilized from 1.2% sodium acetate, 2mg BSA, 0.01mg NaN3
||Reconstitute in 1 mL of PBS (pH 7.4) to achieve an antibody concentration of 100 ug/mL. Centrifuge to remove any insoluble material.
||At least 12 months after purchase at 2-8C (lyophilized formulations). After reconstitution, aliquot and store at -20C for a higher stability. Avoid freeze-thaw cycles
||12 months after purchase