||Adrenocorticotropic hormone (ACTH) is cleaved from the precursor pro-opiomelanocortin (POMC). The hormone is produced and secreted by the pituitary gland and stimulates release of cortisol by adrenal glands.
||See product label
||Porcine Adrenocorticotropic hormone (ACTH) conjugated to BSA
||Corticotropin; ACTH; Pro-opiomelanocortin; POMC;
||P01192 COLI_PIG; P01189 COLI_HUMAN;
||A dilution of 5-10 ug/mL is recommended for immunohistochemistry using formalin fixed and paraffin embedded tissues and for 4% paraformaldehyde fixed frozen tissues. A dilution of 5-15 ug/mL is recommended for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
||Human; mouse; rat; ACTH is highly conserved so cross-reactivity with other species is expected.
||If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule.
The BLAST database can also be used to compare any amino acid sequence between species and between proteins. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please choose carefully, as the sequence you choose may be a precursor rather than the mature protein for example.
||Lyophilised with BSA
||Reconstitute in 0.05 mL of PBS (pH 7.4) to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
||At least 12 months after purchase at 2-8C (lyophilized formulations). After reconstitution, aliquot and store at -20C for a higher stability and at 2-8C with an appropriate antibacterial agent. Avoid freeze-thaw cycles
||12 months after purchase