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Rabbit polyclonal antibody to human NOGO-A (1170-1192): Affinity purified


Catalogue No. R-1611-100
Description Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.
Batch No. See product label
Unit size 100 ug
Antigen A synthetic peptide corresponding to a region (1170-1192) from the C-terminus of human NOGO-A.
Antibody Type Polyclonal
Other Names RTN 4A; Nogo-A; RTN-xL; Reticulon-4; Neurite outgrowth inhibitor; Foocen; NSP;
Accession Q9JK11 RTN4_RAT;
Produced in Rabbit
Purity Affinity purified on antigen column
Applications Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 ug/mL is recommended for WB. A concentration of 0.5-1.0 ug/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Cross-reactivity Rat (WB, IHC); Mouse (WB); expected to react with human due to sequence homology
Blast URL Click here
Form Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Reconstitution Reconstitute in 100 uL of sterile distilled water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage At least 12 months after purchase at 2-8C (lyophilized formulations). After reconstitution, aliquot and store at -20C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date 12 months after purchase
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