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Presenilin-1 (PS-1), Chicken Polyclonal Antibody
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Catalog Number
C-1534
- Product Name Presenilin-1 (PS-1), Chicken Polyclonal Antibody
- Product Description Chicken anti-Presenilin-1 (PS-1) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1;
- Application(s) ELISA, WB
- Antibody Host Chicken
- Antibody Type Polyclonal
- Specificity Human Presenilin 1
- Species Reactivity Human, Mouse, Rat
- Immunogen Description Mixture of two human Presenilin 1 peptides (311-322 and 341-352 aa). Both sequences are highly conserved in human, mouse and rat.
- Conjugate Unconjugated
- Purity Description Affinity-purified
- Regulatory Status For research use only.
Product Info
- Product Description Chicken anti-Presenilin-1 (PS-1) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details WB and ELISA. Suggested dilution of 1:1,000 to 1:4,000. To minimise background staining, a higher concentration of detergent (such as Tween-20) is suggested in the dilution and washing steps. Biosensis recommends that the optimal working dilution should be determined by the end user.
- Target Presenilin-1 (PS-1)
- Specificity Human Presenilin 1
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Chicken
- Antibody Type Polyclonal
- Antibody Isotype IgY
- Conjugate Unconjugated
- Immunogen Description Mixture of two human Presenilin 1 peptides (311-322 and 341-352 aa). Both sequences are highly conserved in human, mouse and rat.
- Sequence KNSKYNAESTER and EAQRDSHLGPHR
- Purity Description Affinity-purified
- Format Liquid. PBS with 0.02% Sodium Azide
- Storage Instructions Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1;
- Uniprot Number P49768
- Uniprot Number/Name P49768 (PSN1_HUMAN)
- Scientific Background Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.