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Cullin-4B (CUL-4B), Rabbit Polyclonal Antibody
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Catalog Number
R-1141
- Product Name Cullin-4B (CUL-4B), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Cullin-4B (CUL-4B) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names CUL-4B; CUL4B; KIAA0695;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Zebrafish; Human; Rat;
- Species Reactivity Human, Rat, Zebra Fish
- Immunogen Description A synthetic peptide (DRDYMERDKENPNQYNYIA) corresponding to a region (877-895) from the C-terminus of human Cullin-4B. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Cullin-4B (CUL-4B) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Western Blotting (WB) and Immunohistochemistry (IHC). A concentration of 1.0 µg/mL is recommended for WB. Human Cullin-4B (isoform 1) has a predicted length of 895 residues and MW of 102 kDa. A concentration of 2.0 µg/mL is recommended for IHC in Zebra fish. Heat mediated antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Cullin-4B (CUL-4B)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Zebrafish; Human; Rat;
- Target Host Species Human
- Species Reactivity Human, Rat, Zebra Fish
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (DRDYMERDKENPNQYNYIA) corresponding to a region (877-895) from the C-terminus of human Cullin-4B. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names CUL-4B; CUL4B; KIAA0695;
- Uniprot Number Q13620
- Uniprot Number/Name Q13620 (CUL4B_HUMAN)
- Scientific Background Cullin-4B is a core component of E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of specific proteins in the cell.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
