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Beta-synuclein, Sheep Polyclonal Antibody

As low as US$327.00
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Catalog Number
S-041
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    Product Info

  • Product Name Beta-synuclein, Sheep Polyclonal Antibody
  • Product Description google Sheep anti-Beta-synuclein Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
  • Alternative Names SNCB
  • Application(s) IHC-Frozen
  • Antibody Host Sheep
  • Antibody Type Polyclonal
  • Specificity Known to be specific for beta synuclein. This antiserum is know to react with human, rat and other rodent beta synuclein.
  • Species Reactivity Human, Rat
  • Immunogen Description A synthetic peptide (IEPLMEPEGSYEDPPQE) as part of human beta synuclein protein (aa: 108-125) conjugated to diphteria toxid has been used as the immunogen.
  • Conjugate Unconjugated
  • Purity Description Whole serum
  • Regulatory Status For research use only.

    Specifications

  • Product Description Sheep anti-Beta-synuclein Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
  • Related Products Beta-Synuclein, Mouse Monoclonal Antibody
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  • Application(s) IHC-Frozen
  • Application Details IHC. A dilution of 1:3000 to 1:8000 is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Beta-synuclein
  • Specificity Known to be specific for beta synuclein. This antiserum is know to react with human, rat and other rodent beta synuclein.
  • Target Host Species Human
  • Species Reactivity Human, Rat
  • Antibody Host Sheep
  • Antibody Type Polyclonal
  • Antibody Isotype Mixed
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (IEPLMEPEGSYEDPPQE) as part of human beta synuclein protein (aa: 108-125) conjugated to diphteria toxid has been used as the immunogen.
  • Purity Description Whole serum
  • Format Lyophilized
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names SNCB
  • Uniprot Number Q16143
  • Uniprot Number/Name Q16143 (SYUB_HUMAN)
  • Scientific Background Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects nerurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Immunohistochemical detection of beta synuclein in rat spinal cord using Sheep antibody to beta synuclein (108-125): whole serum, catalogue no. S-041-100, at a dilution of 1:4000.