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Glutathione peroxidase 3 (GPx-3), Rabbit Polyclonal Antibody
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Catalog Number
R-171
- Product Name Glutathione peroxidase 3 (GPx-3), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Glutathione peroxidase 3 (GPx-3) Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
- Alternative Names Extracellular glutathione peroxidase; GPx-P; GSHPx-3; GPx-3; Plasma glutathione peroxidase; GSHPx-P; GPX3; GPXP
- Application(s) IHC-Frozen
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity This antibody has been shown to be specific for glutathione peroxidase 3 protein (GPx-P) through staining and blocking studies. Human and rat, other species have not yet been ested.
- Species Reactivity Human, Rat
- Immunogen Description A synthetic peptide (FEKGDVNGEKEQKFYTFLKN) corresponding to the amino acids 135-154 of human glutathione peroxidase 3 (GPx-P) conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from glutathione peroxidase 3 (GPx-P) protein in mouse, rat, orangutan and bovine.
- Conjugate Unconjugated
- Purity Description Whole serum
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Glutathione peroxidase 3 (GPx-3) Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
- Application(s) IHC-Frozen
- Application Details IHC, only. A dilution o f 1: 1000 to 1: 5000 is recommended for immunohistochemistry depending on detection method but end user will need to determine dilution to suit application. Antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Glutathione peroxidase 3 (GPx-3)
- Specificity This antibody has been shown to be specific for glutathione peroxidase 3 protein (GPx-P) through staining and blocking studies. Human and rat, other species have not yet been ested.
- Target Host Species Human
- Species Reactivity Human, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype Mixed
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (FEKGDVNGEKEQKFYTFLKN) corresponding to the amino acids 135-154 of human glutathione peroxidase 3 (GPx-P) conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from glutathione peroxidase 3 (GPx-P) protein in mouse, rat, orangutan and bovine.
- Purity Description Whole serum
- Format Lyophilized
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Extracellular glutathione peroxidase; GPx-P; GSHPx-3; GPx-3; Plasma glutathione peroxidase; GSHPx-P; GPX3; GPXP
- Uniprot Number P22352
- Uniprot Number/Name P22352 (GPX3_HUMAN)
- Scientific Background GPx-P belongs to the glutathione peroxidase family which are responsible for the detoxification of hydrogen peroxide. It protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. GPx-P is secreted in plasma and exists as a homotetramer.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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General References
Takahashi K, et al. J. Biochem. 108:145-148(1990).
Chu F.-F, et al. Blood 79:3233-3238(1992).